Weight regain after weight loss drugs is inevitable if lifelong changes aren’t supported
We shouldn’t be surprised by weight regain when people stop taking weight loss drugs if they’re not supported to make effective, long-term lifestyle changes.
Slimming World's Managing Director Lisa Salmon discusses the latest research which has found those taking weight loss drugs can put the weight back on again.
"A recent study presented at the European Congress on Obesity (ECO) from the University of Oxford* highlighted that when people stop taking weight loss drugs, if they don’t maintain a healthy lifestyle, they typically regain some of the weight they lost within a year, with full weight regain expected in under two years.
"It should not come as a surprise that people put weight back on once they stop taking the drugs. With all weight loss methods, if you go back to what you were consuming before, you will regain the weight you’ve lost, and in some cases, sadly more.
"At Slimming World, we strongly believe it's vitally important that wraparound care for any weight loss drugs both supports healthy lifestyle changes around food, drink and physical activity in the moment, and helps people create long-lasting habits that they can maintain well after they stop taking medication.
"While we know that a healthy weight can be achieved, and maintained for life, without taking any medication, our wraparound support is open to all adults, including those who have chosen to take weight loss drugs. We have a growing number of people online and in our groups, who’ve come to us after starting to use the drugs as they understand the importance of making healthy changes alongside them.

At Slimming World, everything we do is geared towards helping our members to make long-lasting changes.
"We differ from weight loss drugs and other weight loss methods in many ways. Our philosophy is based on a deep understanding of how people with a weight problem feel. We believe in the importance of a multi-component approach to weight loss, which is why we offer our members a healthy eating plan, an active lifestyle programme and behaviour change support. We support our members, both in our groups and via our online service, with sophisticated techniques rooted in psychology to help them understand themselves, their triggers and their own personal barriers, and we equip them with tools and strategies to develop lasting, self-determined healthy habits, achieve their weight loss goals and maintain them.
"Slimming World has been a long-time provider to the NHS, through its referral programme which provides people living with overweight or obesity with access to a 12-week weight loss plan via Slimming World, and the NHS Digital Weight Management Programme. An independent economic evaluation by the University of Leeds also found that, Slimming World on Referral, is cost-effective against the standards set by NICE at 12 months and over a lifetime.
"Weight loss drugs have, of course, changed the weight management landscape, but they are a costly method of postponing an ongoing issue, with the knowledge that, without the right support for lasting change, they’re only a temporary solution and not the silver bullet many people have viewed them as.
“If the Government continues to invest huge sums of money into weight loss drugs, they need to ensure they go hand-in-hand with effective wraparound care which supports people to change both their habits around diet and activity, and their mindset so they can be confident they’re spending taxpayers’ money in a way that will provide a return on investment.”
Slimming World was founded by Margaret Miles-Bramwell OBE in Derbyshire in 1969 and has become the UK and Ireland’s leading weight loss organisation with more people choosing to attend a Slimming World group each week than any other weight loss programme. We support hundreds of thousands of people, both in our groups and online, to lose weight and to adopt new habits to stay slim for life.
Over the years our founding principles haven’t changed:
· Our unique programme is based on a powerfully motivating support system called IMAGE (Individual Motivation and Group Experience) Therapy. Underpinned by a deep understanding of the psychology of overweight people, and incorporating the most effective sustainable behaviour change techniques, IMAGE Therapy is designed to inspire and motivate slimmers to make positive changes and to develop new, healthier habits around food and activity.
· Food Optimising is our healthy eating plan, based on the liberating concept of Free Food. We encourage our members to fill up on those foods that are naturally lower in energy density (calories per gram) and also highly satisfying while limiting foods that are highest in fat and sugar and are less satisfying, so they lose weight without ever feeling hungry or deprived and without having to weigh, measure or count everything they eat.
· Our activity support programme, Body Magic helps members to overcome any barriers around exercise. Members choose when to start and they set the pace, finding activities they genuinely enjoy, until regular physical activity becomes an intrinsic part of their daily routine.
At the heart of everything we do lies our passion for treating every member with genuine care, empathy and respect.
We’re proud to work with the NHS, the Office for Health Improvement and Disparities (OHID), The Royal College of Midwives and others to help shape the future of weight management in the UK and Ireland.
For more information about Slimming World’s approach visit slimmingworld.co.uk or slimmingworld.ie
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For the Press Office visit our newsroom or email public.relations@slimmingworld.co.uk
*West, S. et al. (2025). Weight regain following the cessation of GLP-1 RAs for weight management: a systematic review and meta-analysis. Obes Facts 18(S1):368. Presented at the European Congress on Obesity 2025 (ECO2025).